Mat Junoh, Azuraini
(2019)
Fabrication And Characterization Of
Poly(3-Hydroxybutyrate-Co-4-
Hydroxybutyrate)/Gelatin Blend
Scaffolds.
Masters thesis, Universiti Sains Malaysia.
Abstract
The aim of this study is to fabricate a new material by combining hydrophobic and hydrophilic materials. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) has adequate flexibility for medical applications, however, its lack of hydrophilic
properties limits its applications in this field. Therefore, the P(3HB-co-4HB) polymer was blended with gelatin using two different techniques; freeze-drying and electrospinning. The former technique can produce porous scaffolds by manipulating
various parameters including 4HB monomer content, gelatin concentrations, and total
weight of the scaffolds. The surface morphology results of the blend scaffolds at 27
mol%4HB and 50 mol%4HB have high porosity but the porosity of the blend scaffold decreased at 82 mol%4HB.
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