Evaluation of high-dose rate (HDR) radiobiologic dose-equivalent web tool for cervical cancer

Shafizan, Haziq Asyraaf (2024) Evaluation of high-dose rate (HDR) radiobiologic dose-equivalent web tool for cervical cancer. Masters thesis, Universiti Sains Malaysia.

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Abstract

Following successful precision and timing accuracy phases, the next step is a comprehensive evaluation of the web application versus the Microsoft Excel template. Testing with clinical data ensures robustness. Documentation and training for medical physicists are essential. Implementation will start with a pilot group, followed by full-scale deployment. Evaluation of BED and EQD2 values reveals minimal deviations, indicating high comparability. For target tissue, BED deviation is 0.048% and EQD2 is 0.008%. The bladder shows a BED deviation of 0.055% and EQD2 of 0.073%. The rectum has a BED deviation of 0.014% and EQD2 of 0.029%. For the sigmoid, the BED deviation is 0.035% and EQD2 is 0.142%. All deviations are within the 3% tolerance limit. The web application completes the full treatment in 138.69 seconds, compared to 202.67 seconds for Excel, with a TER of 1.46. For the first additional patient, the web application takes 96.84 seconds, while Excel takes 107.11 seconds, giving a TER of 1.11. For the second additional patient, the web application takes 94.77 seconds versus 78.66 seconds for Excel, with a TER of 0.83. Despite occasional exceptions, the web application is generally more time-efficient and reliable.

Item Type: Thesis (Masters)
Uncontrolled Keywords: cervical cancer
Subjects: R Medicine
R Medicine > RC Internal medicine > RC254-282 Neoplasms. Tumors. Oncology (including Cancer)
R Medicine > RC Internal medicine > RC870-923 Diseases of the genitourinary system. Urology
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Thesis
Depositing User: Mr Abdul Hadi Mohammad
Date Deposited: 21 Oct 2024 01:45
Last Modified: 14 Nov 2024 02:14
URI: http://eprints.usm.my/id/eprint/61333

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