Balogun, Wasiu Gbolahan
(2019)
Molecular Toxico-Pathology
Responses Of EUDRILUS EUGENIAE TO 2-
AMINO-l-METHYL-6-PHENYLIMIDAZO[4,5-
bJPYRIDINE (PhIP) AND 2-AMINO-3,8-
DIMETHYLIMIDAZO [4,5-f]QUINOXALINE
(MeIQx).
PhD thesis, Universiti Sains Malaysia.
Abstract
The carcinogenic risks of highly heated proteinaceous foods are at large
associated with the formation of heterocyclic amines (HCAs), evidence in their
substantial presence in the biota. The earthworm Eiidrilus eugeniae (E. eugeniae) is a terrestrial ubiquitous animal, susceptible to toxicity from environmental contamination, and a suitable model for understanding the mechanism of toxic agents
such as HCAs. Thus, this study elucidated the vulnerability of E. eugeniae to HCAs
induced toxicity using a modified OECD TG207 approach.
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