Lamry, Nur Adillah (2021) The effectiveness of tachosil patch as a drainage and haemostatic agent in thyroid and salivary glands surgeries. Masters thesis, Universiti Sains Malaysia.
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Abstract
Objectives: The aim of this study is to evaluate the effectiveness of TachoSil® patch as a drainage and haemostatic agent in thyroid and salivary glands surgeries Method: Twenty-seven patients who undergone thyroid and salivary glands surgeries between June 2018 and May 2020 for benign pathology were included in the study. They were classified into 2 groups; those who did not use TachoSil® patch intraoperatively (known as non-Tachosil group) and those who used TachoSil® patch intraoperatively (known as Tachosil group). Parameters such as duration of surgery, estimated blood loss, post-operative drain amount, duration of drain and duration of hospital stay were used to measure the outcomes in both groups. Result: After 24 hours of surgery, mean drainage volume was reduced in Tachosil group (20mL vs 45mL in non-Tachosil group, p=0.049). Drain removal occurred earlier in the Tachosil group (2 days, as opposed to 2.5days in non-Tachosil group, p=0.045), which resulted in a shorter duration of hospital stay (2 days, as opposed to 2.5d days for non- Tachosil group). Conclusion: This study demonstrated that TachoSil® is beneficial in reducing postoperative drainage volume, which lead to reduction of drain duration, and eventually a reduction in hospitalisation time. Considering that it was significant in providing haemostasis intra-operatively, a bigger sample size future study is needed to adequately assess its effectiveness.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | tachosil patch, haemostatic agent |
| Subjects: | R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research R Medicine > RD Surgery |
| Divisions: | Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Thesis |
| Depositing User: | Mr Abdul Hadi Mohammad |
| Date Deposited: | 19 May 2024 07:21 |
| Last Modified: | 19 May 2024 07:21 |
| URI: | http://eprints.usm.my/id/eprint/60609 |
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