Mohamed, Mazrah
(2021)
Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates.
Masters thesis, Universiti Sains Malaysia.
Abstract
Background: Transcutaneous bilirubinometer is a portable, painless and non-invasive
device to measure bilirubin. This study aims to investigate the reliability of Dräger Jaundice
Meter JM-105 for the screening of neonatal jaundice in Malay neonates.
Methods: Prospective cross-sectional study conducted in a tertiary university hospital
involving 130 jaundiced neonates who required serum bilirubin determination from day 2 to day
7 of life. Paired bilirubin samples of total serum bilirubin (TSB) and transcutaneous bilirubin
(TcB) were obtained. TcB were measured at the neonates’ forehead and sternum. The TcB were
measured using JM-105.
Results: There were 130 paired samples of TSB and TcB. The mean TSB was 232
μmol/L. The mean TcB measured at forehead and sternum were 222 μmol/L and 223 μmol/L,
respectively. The mean difference between TSB and TcB was 10 μmol/L at forehead and 9
μmol/L at sternum. Strong positive correlation between TSB with mean TcB forehead (r=0.82)
and TcB sternum (r=0.80), and strong correlation (r=0.91) between TcB forehead and TcB
sternum.
Conclusion: Our study demonstrated strong correlation between TcB values and TSB
values. TcB measured at forehead or sternum is a good alternative as a non-invasive screening
tool for non-severe hyperbilirubinemia in Malay neonates.
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