Intan Juliana, Abd Hamid
(2011)
A randomised controlled trial of single phototherapy with reflecting curtains and
double phototherapy in term newborns with
hyperbilirubinemia.
Masters thesis, Pusat Pengajian Sains Perubatan.
Abstract
To compare the efficacy of single phototherapy with reflecting curtains and double
phototherapy in treating neonatal jaundice. Randomized controlled clinical trial. NICU Hospital Universiti Sains Malaysia, Kelantan, Malaysia. Term newborns with severe neonatal jaundice in the first 2 weeks of life. Single phototherapy with reflecting curtains (intervention group, n=63) was
compared with double phototherapy (control group, n=54). The primary outcome was the mean difference in total serum bilirubin measured at
baseline and after 4 hours of phototherapy. The secondary outcome was the duration
of phototherapy. The mean (standard deviation) decrease in serum bilirubin after 4 hours of
phototherapy in the intervention group was 24.16 (27 .87) ~mol/L and the control
group was 21.11 (24.69) ~mol/L (p 0.536), statistically not significant. Cox
proportional hazards regression analysis indicated that there was no statistically
significant difference in duration of phototherapy in both intervention (SPRC) and
control (DP) (.1 change 1.641; p 0.200; hazard ratio 0.784; 95% confidence interval
0.542 to 1.136). There were no other significant adverse events noted. This study suggested that single phototherapy with reflecting curtains are equally
effective as double phototherapy in treating severe neonatal hyperbilirubinaemia.
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