Kok Wei, Wee
(2009)
4th International Conference on child and adolescent psychopathology.
Other.
Pusat Pengajian Sains Kesihatan.
(Submitted)
Abstract
To assess and compare working memory of children with
Attention Deficit Hyperactivity Disorder (ADHD}, their sibling and those
children with other chronic medical illness.
Method: By using a cross-sectional design, 57 subjects were recruited
through universal sampling from Hospital Universiti Sains Malaysia.
a) ADHD group (n= 21),
b) siblings of ADHD children group {n=15), and
c) non-ADHD children with chronic medical condition as the control group
(n = 21}. All subjects were aged between 6 and 15 years, and ADHD was
diagnosed according to DSM-IV-TR. Those with other psychiatric comorbidity
or Intelligence Quotient (IQ) Jess than 70 were excluded. Three
tests from the Working Memory Test Battery for Children were used for
assessment. Digit Recall was used for assessment of the phonological loop
component, Maze Memory test for the visuospatial sketch pad component
and Backward Digit Recall for the central executive component.
Result: ADHD children and their siblings showed similar impairment and
both differed from the control group on the Maze Memory test. ADHD
children also showed Impairment in Digit Recall test, however the sibling
group did not differ from the control group on this test. The score of
Backward Digit Recall did not show any significant difference between the
3 groups.
Conclusion : Impairment of the visuospatial sketch pad component of
working memory seems to cluster in ADHD children and their siblings.
Thus, Impairment of vlsuospatial sketch pad component may point
towards an endophenotype of ADHD.
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