Ashari, Noor Suryani Mohd
(2010)
Association between common
allergens and symptoms among
allergic rhinitis patients in HUSM.
Other.
Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia.
Abstract
Allergic rh1nit1s 1s the mo$'1 common allerg1c d1sease affecting an estimated four m1lhon
people in Malaysia. · Althqugh this disease is not usually severe disease, it significantly
alters the social life of patients and affects school learning performance as well as work
productivity. This study was done to determine levels of allergen specific
Immunoglobulin E assay, in allergic rhinitis patients in Hospital Universiti Sains Malaysia
(HUSM), Malaysia and to determine the severity of symptoms before proceed with
evaluation of possible association between this parameter with severity of allergic
rhinitis. In this cross sectional study, total and specific lgE to 28 types of allergens were
measured in serum samples from 128 allergic rhinitis patients. The interviewer guided
questionnaire was used to evaluate the severity of symptoms using ARIA criteria. In this
study we found that Dermatogoides farinae (97%) was the most common allergen.
Regarding the symptoms, sneezing (99.2%) was found to be the most common clinical
symptoms. We also found a significant association between the specific lgE levels and
the severity of allergic rhinitis for Dermatogoides farinae (p=0.024), Dermatogoides
pteronyssinus (p=.039), cockroach (p = 0.038) cat (p = 0.042) and latex (p = 0.044) .
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