In vitro cytotoxicity evaluation of locally produced dental porcelain

Husein, Adam (2011) In vitro cytotoxicity evaluation of locally produced dental porcelain. In vitro cytotoxicity evaluation of locally produced dental porcelain.

[img]
Preview
PDF - Submitted Version
Download (241kB) | Preview

Abstract

The in vitro cytotoxic potential of locally produced dental porcelain was evaluated in this study. The cellular response of human osteoblast and MRC-5 cell lines were assessed using MTT assay by incubatiog with the fluid extract of dental porcelain powder and dental porcelain discs (direct test). Aging process was carried out by submerging the discs into 3% Bovine Serum Albumin (BSA) solution. Tests on extracts showed that the material was significantly different from the control at a concentration of 250 mg/ml. Direct test showed thRt the material after aging was not significantly different from the control with a mean (SD) of 89.2(13.4) %, whereas, it was significantly different from the control before conditioning of BSA with a mean (SD) of 88.5(12.1) %. However, the dental porcelain caused mild suppression of succinate dehydrogenase activity (<25%), which is considered to be accepted clinically and hence can be ranked as being non-cytotoxic or mildly cytotoxic.

Item Type: Article
Uncontrolled Keywords: porcelain
Subjects: R Medicine > RK Dentistry
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Pergigian (School of Dental Sciences) > Article
Depositing User: Mr Abdul Hadi Mohammad
Date Deposited: 02 Sep 2021 03:21
Last Modified: 02 Sep 2021 03:21
URI: http://eprints.usm.my/id/eprint/49770

Actions (login required)

View Item View Item
Share