Zaidi, Ahmad Al-Hafeez Ahmad
(2020)
Outcomes of endoscopic therapy for bleeding peptic ulcers ; a retrospective study in Hospital Serdang.
Masters thesis, Universiti Sains Malaysia.
Abstract
Background and objectives: Endoscopic therapy remains the mainstay in treatment of
upper gastrointestinal bleeding (UGIB). Despite the advancement in endoscopic
therapy, the mortality rate for UGIB has remained constant at about 10% for the past
few decades. This study aims to determine the prevalence of outcomes post endoscopic
therapy in bleeding peptic ulcers.
Methods: This is a retrospective record review of patients who underwent emergency
upper endoscopy for UGIB from March 2014 to March 2019 in Hospital Serdang,
Selangor. Data was collected from endoscopic suite records and the prevalence of
permanent haemostasis, re-endoscopy, angio-embolization, surgery and 30-day
mortality was calculated.
Results: A total of 204 patients who underwent emergency upper endoscopic therapy
for UGIB were included in our study. More than half of the patients 113 (55.4%)
achieved permanent haemostasis after initial endoscopic therapy whilst 84 (41.2%) had
to undergo re-endoscopy due to re-bleeding ulcer. A small percentage had to undergo
surgery 10 (4.9%) while only 3 (1.5%) underwent angio-embolization. Out of 204
patients included, there was 34 (16.7%) mortalities and the median length of stay was 5
days.
Conclusion: From our study, we can conclude that permanent haemostasis is the
outcome with highest prevalence after endoscopic therapy for UGIB in our centre.
However, we should strive to reduce our rate of re-endoscopy as it is not up to par with
data from other developing countries.
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