Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis

Mohd Redhuan, Mohd Noor (2008) Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis. Other. Universiti Sains Malaysia. (Submitted)

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Abstract

The struggle to determine susceptibility genes for complex disorders has stimulated geneticists to develop new approaches. The genetic markers rapidly superseded by microsatellites since they prolifically throughout the genome and are highly variable in repeat length and polymorphisms. The Negritos, believed to be the first aborigines arrived at Peninsular Malaysia, somewhat I 0,000 years ago was thought to be related to Andaman islanders and Nicobar Islands. They are divided into six groups, namely Kensiu, Bateq, Mendriq, Jahai, Lanoh and Kintak. In this study, an attempt was made to optimize the locus D 198220 for GeneS can Analysis purpose. Marker was selected from Genethon Microsatellite Map (http://www.genlink.wustl.edu/genethon_frame/). DNA was extracted from the samples collected from three Negrito Tribes in Kelantan: Jahai, Mendriq and Bateq. A series of PCR optimization were done and run on the ABI 3100 capillary based genetic analyzer. PCR was then amplified on the Mendriq population in order to examine the PCR condition optimized. iii

Item Type: Monograph (Other)
Uncontrolled Keywords: Complex disorders
Subjects: R Medicine > R Medicine (General)
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Monograph
Depositing User: Mr Husnan Budin
Date Deposited: 13 Apr 2021 03:42
Last Modified: 13 Apr 2021 03:42
URI: http://eprints.usm.my/id/eprint/48862

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