Shafii, Noorazliyana
(2020)
Effect of oral supplementation of channa striatus extract on total antioxidant status during wound healing in post lower segment caesarean section women.
Other.
International Medical Journal.
(Submitted)
Abstract
Objectil>e: C. striatus has been suggested to have antioxidant and anti-inflammatory properties for wound healing. This study
was conducted to determine the level of Total Antioxid ant Status (TAS) and the effectiveness of or al suppl emen tation of
C. striatus extract in post Lower Segment Caesarean Section (LSCS) patients during wound healing.
Design: This was a r andomized; double blinded, pl ace bo-co ntr oll ed study among post LSCS women conducted in
Department of Obstetri c and Gynaecology, Hospital Universiti Sains Malaysia from March 2010 to December 20 12.
Material and Methods: A total of 39 patients from C.striatus and 34 patients from pl acebo group wet·e in cluded in thi s study.
After randomization, the treatment group consumed 500 mg of freeze dried C. striatus extract daily while the placebo group consumed
500 mg of placebo (maltodextr in) daily for 6 weeks. For each subject, venous bloods for TAS were taken postoperatively
at day I, day 3, week 2, week 4 and week 6. Repeated measure for analysis of variance (ANOVA) was used to determine the
changes ofTAS between and within both groups throughout the 6 weeks intervention.
Result.~ : The result suggested an in crement of TAS level within C.striatus group from second week postoperative onwards
which might involve in th e enh ancement of wound healing.
Conclusion: The ad ministration of C.striatus extract has beneficial effec t dur ing wound healing by enhancing the process in
post-oper ative LSCS women
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