Amnah, Ab Halim
(2006)
Burn wound dressing using honey hydrogel
versus hydrogel.
Other.
Universiti Sains Malaysia.
(Submitted)
Abstract
Burn injury results in either the loss or disruption of skin functions. Skin plays its
main roles in protection, immunological, homeostatsis and thermoregulation,
neurosensory, etc .. Honey is believed to be the best ancient medicine to cover
wounds that causes by burn either thermally or electrically. The unique ingredients
of honey acts by inhibiting gram positive and negative bacteria, promotes
epithelialization and burn healing. This project is to assess the impact of honey on
wound dressing for burn wound treatment. The study compared the effectiveness
of honey hydrogel in bum wound healing with hydrogel agar as a control. Burn
wounding rats were chosen as the study model. Twelve female Sprague-Dawley
rats were divided into two equal of size n=6 and kept in same room with same
food and environment. The operation was done under aseptic technique, in sterile
condition. At first, rats were anaesthetized with ketamine injection and disinfectant
with alcohol and povidone iodine. Burn lesion was created by applying hot metal
plate for ten seconds on the back of the rats. The first group was treated by honey
hydrogel while the other group was covered by hydrogel agar only. Honey
hydrogel is actually a hydrogel whereby 6% of the water content replaced with
honey. They were supervised daily and on the 7th and 14th day postoperatively the burn lesion was measured. The average of burn wound size on day 14 for honey
hydrogel and hydrogel was 0.24 em 2 and 0.64 em 2 respectively. This indicates
that wound treated with honey hydrogel contracts faster and seem to be more
effective than hydrogel as it provides moist and good bedding for epithelialisation
that can heals the faster.
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