Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet

Liew, Kai Bin (2017) Investigation Of Taste Masking Techniques And Development Of Dapoxetine Hcl Orally Disintegrating Tablet. PhD thesis, Universiti Sains Malaysia.

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Abstract

In the development of orally disintegrating tablets (ODT), palatability plays a critical role. As there were hardly any reported studies on taste masking of drugs which cause burning sensation on oral mucosa and is bitter in taste, dapoxetine HCl was chosen for the study. Various taste masking techniques, namely complex formation with ion exchange resin, coating with pH sensitive polymer, coating with hydrophilic polymer, chemical modification, addition of sweetener and flavour, inclusion complexation and blending with inorganic compound, were investigated.

Item Type: Thesis (PhD)
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: Pusat Pengajian Sains Farmasi (School of Pharmacy) > Thesis
Depositing User: Mr Aizat Asmawi Abdul Rahim
Date Deposited: 11 Jan 2021 02:42
Last Modified: 11 Jan 2021 02:42
URI: http://eprints.usm.my/id/eprint/48065

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