Yeo, Hui Yee
(2017)
Economic Evaluation And Willingness To Pay (Wtp) Elicitation Of Dengue Vaccine In Malaysia.
Masters thesis, Universiti Sains Malaysia.
Abstract
Dengue disease poses great health and economic burden in Malaysia. This study was divided into two phases. Phase-1 evaluated the impact and cost-effectiveness of dengue vaccine employing a dynamic-transmission mathematical model from both public provider and societal perspective. The model integrated Malaysia-specific epidemiological data, pooled efficacy and long-term safety data from phase-III clinical studies, and sensitivity analyses to refine the estimates from previous studies. Phase-2 assessed the acceptance and willingness-to-pay (WTP) value of dengue vaccine among Penang general population utilizing a cross-sectional, contingent-valuation approach. A double-bounded dichotomous-choice approach was applied in eliciting the WTP amount via bidding game method. The mean WTP value and the factors affecting the WTP value were determined by a parametric two-part model (TPM). The association between dengue vaccine acceptance and its determinants was analysed by a univariate logistic regression model.
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