Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231

Siah, Poh Chiew (2017) Effect Of Red Onion (Allium Cepa) Peel Extracts And Fractions On Cell Proliferative And Metastatic Activities In Mda-Mb-231. PhD thesis, Universiti Sains Malaysia.

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Abstract

The present study was conducted with the objective to study the anti-cancer property of red onion (Allium cepa) peel extracts and its fractions by investigating the effects in MDA-MB-231, MCF-7 and Cal-27. The effects of red onion peel extracts and its fractions in the anti-proliferative activity, induction of apoptosis - programmed cell death and anti-metastasis were studied. In addition, the involvement of Wnt signalling pathway in the anti-cancer activity of red onion peel extracts and its fractions was also investigated. In the results, the extracts (E1 and E3) and fractions (F1, F2, F1W and F2W) showed promising inhibitory effect on cell viability of MDA-MB-231.

Item Type: Thesis (PhD)
Subjects: Q Science > QK Botany > QK495 Angiosperms
Divisions: Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM) > Thesis
Depositing User: Mr Aizat Asmawi Abdul Rahim
Date Deposited: 26 Oct 2020 07:17
Last Modified: 26 Oct 2020 07:17
URI: http://eprints.usm.my/id/eprint/47773

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