Singh, Gurmit Kaur a/p Sardara
(2006)
Assessment of volume reduction of uterus and uterine fibroids using arterial embolization.
Masters thesis, Universiti Sains Malaysia.
Abstract
Objective: The objective ofthis study was to assess the volume reduction ofthe uterus and
the uterine fibroid using artery embolization for patients with symptomatic fibroids. This
study was also aimed to determine the complications of uterine artery embolization and to
document improvement ofthe symptoms post UAE.
Materials and Methods: Twelve patients had bilateral uterine artery embolization(UAE)
for symptomatic uterine fibroids. This study was conducted over a period of 21 months in
Hospital Universiti Sains Malaysia. All the patients had a pre-embolization Magnetic
Resonance Imaging (MRI) and ten of the patients had a repeat MRI three months post
uterine artery embolization. One patient developed bleeding post-embolization and had a
hysterectomy done. The second patient got pregnant immediately post-embolization and
delivered a healthy term baby girl by caesarean section. Volume of the uterus and the
dominant fibroid was calculated pre-embolization and post-embolization. Comparison was
done between the volume pre-embolization and post-embolization, to see the percentage of
reduction. Symptom improvement and the complication due to uterine artery embolization
were also noted.
Results
Results show fibroid volume reduction median to be 63.82% with interquartile range of
36.78 and uterine volume reduction median to be 47.85% with interquartile range of 36.99.
Symptom improvement at three months was 85-100%. The complications which occurred
were mostly minor complications with one major complication requiring hysterectomy.
Conclusion:
UAE is an effective and a safe method of treatment for symptomatic uterine fibroids. There
is significant symptom and volume reduction of both the uterus and the dominant fibroid.
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