Abidin, Mohd Radhwan
(2018)
Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound.
Masters thesis, Universiti Sains Malaysia.
Abstract
Background: MR-HIFU is a technological breakthrough for non-surgical approach for
treating tumour. MR-HIFU is safe with many advantages however complications may occur,
at target and the near-field region. Specific ultrasound setup at MR-HIFU console must be
made prior to ablation process, which can affect the near-field temperature. The purpose of
this study was to investigate how intersonication cooling time and sonication power influence
the near-field temperature.
Methodology: Philips QA phantom was used for ablation. A total of 100 ablations were
made with different intersonication cooling time, which are 30 s, 60 s, 90 s and 120 s and
different sonication power, which are 40 W, 80 W, 120 W, 160 W and 200 W. The near-field
region was taken at 2cm from the base of phantom. The data were evaluated using statistical
analysis. Level of significance was determined (p < 0.05).
Results: There was no significant correlation between intersonication cooling time and the
near-field temperature, with p = 0.089. However, there is a significant correlation between
sonication power and the near-field temperature with p = 0.001. Regression analysis indicates
that the sonication power significantly predicted the temperature changes [R2 = .416, F(1,18)
= 14.533, p = .001]
Conclusion: There is no relationship between intersonication cooling time with near-field
temperature. However, there is relationship between sonication power and near-field
temperature.
Actions (login required)
 |
View Item |
