Effects of Vitex pubescens on pregnant rats

Subramanian, Premavathy (2004) Effects of Vitex pubescens on pregnant rats. Other thesis, Universiti Sains Malaysia.

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The herbal plant Vitex pubescens was evaluated for it effects on pregnant albino rats. 54 female rats were used for this study. The rats were divided into control group and treatment group. Extract of the plant was prepared with distilled water by using soxhlet apparatus in pharmacology laboratory. The plant extract was administered orally by means of a gavage from day I to day 7 of pregnancy. Out of I2 rats in each group, 6 were laparotomized under ether anaesthesia on day 1 0 of pregnancy. Both the horns of uterus was observed for number of fetus or resorption site and allowed to full term pregnancy. Number of fetus was compared with the number of pups delivered. The remaining 6 rats were used for histological study to confirm the activity of the extract. Result of the study showed that aqueous extract of Vitex pubescens did not show efficacy as an antifertility agent. However, late resorption was observed in rat, which treated with 1 Omg/kg and I OOmg/kg of Vitex pubescens extract.

Item Type: Thesis (Other)
Uncontrolled Keywords: herbal plant
Subjects: R Medicine
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Kesihatan (School of Health Sciences) > Thesis
Depositing User: Mr Abdul Hadi Mohammad
Date Deposited: 11 Mar 2020 04:30
Last Modified: 11 Mar 2020 04:30
URI: http://eprints.usm.my/id/eprint/46481

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