Noor, Shah Reza Johan
(2005)
A study of chlamydial infection in pregnancy in Hospital Kota Bharu, Kelantan.
A study of chlamydial infection in pregnancy in Hospital Kota Bharu, Kelantan.
(Submitted)
Abstract
( .'h/amydia trachoma/is infection is the most common curable bacterial infection, and is
now the most common sexually transmitted disease worldwide. World Health Organisation .
fi gures estimated that 89 million new cases of geni tal chlamydia! infections· occur.rea;,'in
1995, highligh ting the worldwide prevalence of infections and the economic hurd.en .on
hca rthcare delivery. For pregnant women, this infection has been associated with morbidity
l()r both the mother and the newborn.
Oh;ectives: This study was undertaken with th e objectives to detennine the prevalence of
_ge nit<tl Chlamydia trachomatis inrection in pregnancy among the attendees of Antenatal
Clinic of ll ospi tal Kota Bhant. Kelantan so as to ascenain ,,·hether universa l sc reen ing is
needed or not. The other objective is to observe the c!Tccti vencss of treatment or
chlamydia! infection with one-week course of erythromycin steartltc SOOmg qid .
Methodology 44 0 pregnant women (age ran g~ 17 to 48 years old), in the li rst to thi rd
ltllllester, attending the antenatal clinic of llospital Kota 11haru, Kelantan were tested for
( "/ilamydw trachoma fl s. Endocervical swabs were colkctcd fo r ( "hlamydia trac!Jo111ut1.\
diagnosis by Direct f- luorescence anti gen detection (DF A) technique.
J?esu/ts: Out of 440 tested women, four were positive, giving the prevalence rate of 0.9%.
No valid stati sti cal analysis can be made with regards to the age, gravidity, parity,
socioeconomic status, education level, history of pr~maturity .or stillbirth or abortion
between the positive and negative group because of ~he small number of wornen with
positive results. All the four women with positive results were retested afler treatment and
all of them were cleared. However, small numbt:;r of patients again, precludes further
statistical analysis.
Conclusion: As the prevalence rate of genital Chlamydia trachoma/is infection in antenatal · ·
populat.ion of Hospital Kota Bharu is very low, there is no need for universall screening to
detect this infection. All of the women with positive chlamxdial tests were asymptomatic.
Therefore diagnostic testing based on clinical findings is unreliable.
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