Al-Joudi, Fawwaz Shakir Mahmoud
(2004)
Immunohistochemical study of breast cancer antigens (part 1).
Immunohistochemical study of breast cancer antigens (part i).
(Submitted)
Abstract
Survivin has been characterized as a member of the family of inhibitor of
apoptosis proteins (lAP). It is a 16.5 kD protein made up of 142 amino acids. Survivin is
expressed in the G2/M phase of the cell cycle. It has been previously sho\vn to be
expressed in a large number of cancers, and its expression has been associated with the
aggression of tumors, or with the poor survival of cancer patients.
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