Zainuddin, Nik Aida Diana Nik
(2004)
Studies on the antifungal effect of cymbopogon nardus (serai wangi) on several fungi and yeasts.
Masters thesis, Universiti Sains Malaysia.
Abstract
Antifungal studies of Cymbopogon nardus were carried out against several different
fungi and yeast. Cold extraction method employing organic solvents was used in this
study. The filtered aqueous methanolic extract of the leaves was sequentially
extracted with n-hexane, chloroform and ethanol respectively. Candida albicans,
Candida g/abrata, Candida tropicalis and Cryptococcus neoformans were selected as
test organisms. The chloroform extracts of Cymbopogon nardus was active against
Candida albicans, Candida glabrata and Candida tropicalis giving a clear zone of 0. 7-
0.8 em at different concentrations (0.01 mg/ml, 0.1 mg/ml and 1.0 mg/ml). The nhexane,
ethanol and methanol extract did not show any inhibitory activity against the
microorganisms tested except for Candida glabrata, where a clearing zone of 0.6-0.9
em was noted for the ethanol and methanol extracts at different concentrations. nHexane,
chloroform, ethanol and methanol extracts were active against
Cryptococcus neoformans at all the concentration tested. However, the growth
inhibitory effect of all the extracts are insignificant compared to the antibiotic
Amphotericin B.
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