S., Panneerchelvam and Norazmi, Mohd Nor
(2003)
Gene frequencies of D16S539, D7S820 and D13S317
STRs alleles in random malay population.
Gene frequencies of D16S539, D7S820 and D13S317 STRs alleles in random malay population.
Abstract
DNA analysis of biological materials for individualization purposes has
become the norm In crime investigation. A number of different DNA markers exist for
individualization of biological stains. However STR based DNA profiling(microsatellite
polymorphism) is the most widely used technique in personal identification. Personal
identification tests involve mathematical probabilities of genetic markers to ascertain the
likelihood of probability for a conclusive answer. In this study distribution of allele
frequencies of three STR polymorphic genetic markers-viz .,D13S317,D7S820 and
0168539 were studied in random malay population of Malaysia. The observed genotypic
distribution showed no significant deviation from Hardy-weinberg equilibrium . The data in
the present study have been compared with recently published data as reported in the
liuterature for various population groups. The data on the three validated STRs will be
useful in parentage testing and personal identification in criminal and immigration
cases.
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