Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation

Abdul Halim, Nur Shuhaidatul Sarmiza (2018) Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation. PhD thesis, Universiti Sains Malaysia.

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Abstract

Cell-based therapy of mesenchymal stem cells (MSCs) has been shown to enhance the endogenous repair process by increasing the limited regenerative capacity of the lung in chronic lung disorders as well as following injury. However, the underlying cellular and molecular mechanisms of MSCs to enhance airway regeneration and repair are remain unclear. This study was aimed to investigate the effect of delivering human adipose-derived MSCs (hAD-MSCs) alone and in combination with vasculoprotective factor, the ANGPT1, by aerosol technique in a rabbit model of asthma related-airway inflammation.

Item Type: Thesis (PhD)
Subjects: R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions: Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis
Depositing User: ASM Ab Shukor Mustapa
Date Deposited: 24 Jul 2019 01:07
Last Modified: 24 Jul 2019 01:07
URI: http://eprints.usm.my/id/eprint/45036

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