Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study

Isa, Asmida (2014) Molecular Cytogenetics Of Myelodysplastic Syndrome – Hospital Based Study. Masters thesis, Universiti Sains Malaysia.

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Abstract

Myelodysplastic Syndrome (MDS) is a haematological condition characterised by hypercellular bone marrow and low peripheral blood counts. The objectives of this study were to identify chromosomal aberration using conventional cytogenetics and array comparative genomic hybridisation (array-CGH) in MDS patients and correlate with its’ haematological findings. A total of 8 patients were recruited. Cytogenetic mresults revealed six normal karyotypes, a karyotype with structural abnormalities (del(5)(q13q33) and a karyotype with complex rearrangement (t(1;11), t(2;11), del(4p), del(5p), del(9p)). By array-CGH technique, known cytogenetic aberrations, complex chromosome aberrations and rare/cryptic aberrations (<5 Mb) were detected.

Item Type:	Thesis (Masters)
Subjects:	R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions:	Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis
Depositing User:	ASM Ab Shukor Mustapa
Date Deposited:	22 Jul 2019 02:52
Last Modified:	22 Jul 2019 02:52
URI:	http://eprints.usm.my/id/eprint/44991

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