Othman, Zahiruddin and Ahmad, Fazil and Halim, Ahmad Shahril Abdul and Ismail, Nurul Nadia (2014) Clozapine-Induced Myocarditis and Pericarditis. International Medical Journal, 21 (6). pp. 539-540. ISSN 1341-2051
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Abstract
Objective: Clozapine is known to cause cardiac side-effects, including myocarditis, pericarditis and cardiomyopathy. A 50-year-old Malay man with schizoaffective disorder and tardive dyskinesia who developed transient tachycardia, low blood pressure and fever after 17 days of starting clozapine was studied. Result: Elevated creatinine kinase at 532 U/l along with WBC and neutrophil count at 21.40 and 16.83 x 1071 respectively indicated an acute myocarditis. Additionally, pericardium involvement was suggested by V1-V4 ST elevation and absence of T wave inversion. Conclusion: The emergence of tachycardia, low blood pressure and fever in patient who is recently started on clozapine treatment should be investigated for cardiac complications. Old age and concomitant treatment with sodium valproate possibly increased the risk of clozapine-induced cardiac side-effects
| Item Type: | Article |
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| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Article Zoom Profil Pakar (Expert Profile) > Zahiruddin Othman (Medical Sciences) |
| Depositing User: | Administrator Automasi |
| Date Deposited: | 23 Jun 2019 04:40 |
| Last Modified: | 23 Jun 2019 04:41 |
| URI: | http://eprints.usm.my/id/eprint/44712 |
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