Shafin, Nazlahshaniza and Othman, Zahiruddin and Zakaria, Rahimah and Hussain, Nik Hazlina Nik (2014) Tualang Honey Supplementation Reduces Blood Oxidative Stress Levels/Activities in Postmenopausal Women. ISRN Oxidative Medicine, 2014 (364836). pp. 1-4. ISSN 2314-6400
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Abstract
his study aimed to investigate the ability of Tualang honey (TH), a phytoestrogen, to reduce blood oxidative stress levels/activities in postmenopausal women and compared the efects with the standard estrogen progestin therapy (EPT). A total of 78 healthy postmenopausal women were randomly assigned to one of two groups; EPT group received Femoston conti 1/5 (1mg 17�- estradiol and 5mg dydrogesterone), and TH group, received 20 g of TH supplement daily for 16 weeks. he reduced glutathione to oxidized glutathione ratio (GSH:GSSG), plasma glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD), and �-hydroxynonenal (�-HNE) levels/activities were measured at pre- and postinterventions using commercially available kits. he plasma GPx and CAT activities were notably increased, and plasma �-HNE level was signiicantly decreased in postmenopausal women who received EPT and TH supplementation. TH supplementation for 16 weeks was able to reduce blood oxidative stress levels/activities of postmenopausal women comparable to those who received EPT. hus, TH has a potential to be used as antioxidant therapy to combat oxidative stress-induced neurodegenerative diseases.his trial is registered with NCT01300676.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Article Zoom Profil Pakar (Expert Profile) > Zahiruddin Othman (Medical Sciences) |
| Depositing User: | Administrator Automasi |
| Date Deposited: | 04 Jun 2019 04:11 |
| Last Modified: | 04 Jun 2019 04:11 |
| URI: | http://eprints.usm.my/id/eprint/44530 |
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