Early Intervention in Psychosis: Efficacy of the Screening Program

Razali, Salleh Mohd and Othman, Zahiruddin and Abidin, Zarina Zainal and Yassin, Mohd Azhar Mohd (2011) Early Intervention in Psychosis: Efficacy of the Screening Program. International Medical Journal, 18 (2). pp. 117-120. ISSN 1341-2051

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Aims; To screen and detect individuals at ultra high risk (UHR) for psychosis and evaluate the efficacy of a screening program Methods: This is a two-stage study involving relatives of patients with schizophrenia. The first degree relatives were screened with the GHQ-12 and non-first degree relatives were additionally screened with the selfconstructed screening questionnaires (SQ). All the positive suhjects from the initial screening will he proceeded to the second stage screening. Results: Fifteen (13.5%) of 111 subjects were positive in the first stage. After the second stage screening, only 3 (2.7%) were positive (UHR suhject). Two (2.6%) cases were first degree relatives and the other one (3%) was non-first degree relatives. Although the majority of the positive suhjects in the initial screening were detected through the GHQ-12, only one of them was positive in the second stage. Conclusion: Screening of genetic risk relatives of schizophrenia is feasible. The detection rate of subject at UHR was much lower than expected, especially among first degree relatives. The higher detection rate among non-first degree relatives is contrihuted by the addition of the SQ. The GHQ-12 is not suitable for screening in early psychosis; it should he comhined with other screening instruments.

Item Type: Article
Uncontrolled Keywords: early psychosis, early intervention, prodromal symptoms, schizophrenia, GHQ
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Article
Zoom Profil Pakar (Expert Profile) > Zahiruddin Othman (Medical Sciences)
Depositing User: Administrator Automasi
Date Deposited: 29 May 2019 08:49
Last Modified: 29 May 2019 08:49
URI: http://eprints.usm.my/id/eprint/44430

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