Tharmathurai, Sangeetha
(2016)
Quality of life and depression in patients with primary open angle glaucoma using Malay version of glaucoma quality of life 36 and Malay version geriatric depression scale 14 questionnaires.
Masters thesis, Universiti Sains Malaysia.
Abstract
INTRODUCTION
Glaucoma is a chronic disease requiring life long treatment. Quality of life (QoL) is
often under emphasized during the course of glaucoma management. Understanding
the quality of life and detection of early depression at different severity stage of
POAG not only helps in coping with the disease but also in customization of the
management. There is still a wide gap in understanding the QoL and depression in
elderly with POAG in Malaysia.
OBJECTIVE
To evaluate quality of life and depression in patients with primary open angle
glaucoma using the Malay version of the Glaucoma Quality of Life- 36 (Glau-QoL
36) and malay version Geriatric Depression Scale 14 (mGDS 14) questionnaires. This
study also aims to compare the QoL and depression with severity of POAG. The
potential correlation between QoL and depression was also studied.
METHODS
A cross sectional study was conducted in Hospital Universiti Sains Malaysia,
Kelantan and Hospital Selayang, Selangor between July 2014 and February 2016.
POAG patients who were ≥ 60 years old at the time of recruitment had mLOCS II
grade 1 or less, underwent cataract or trabeculectomy surgery at least 3 months prior
and were on medical or combined medical and surgical treatment. Severity of POAG
was based on modified Advanced Glaucoma Intervention Study (AGIS) based on two
reliable reproducible Humphrey visual field SITA program 24-2 analysis. Face to face
interview was conducted using validated Bahasa Malaysia version of GlauQol 36 and
mGDS 14 questionnaires.
RESULTS
A total of 360 patients were recruited. Majority of recruited patients were between
ages 60-67 (38.3%). Overall 64 (17.8%) have mild POAG, 93 (25.8%) have moderate
POAG, 115 (31.9%) have severe POAG and 88 (24.4%) have end stage POAG.
Majority of the recruited patients were not working (88.9%) and live with their
families (68.1%). There was significant association between GlauQoL 36 score
among POAG patients according to severity and domains: daily living, driving,
physiological well being, self image, anxiety, burden of treatment and confidence in
healthcare. Increased severity of POAG was associated with dectresed quality of life
in all GlauQoL 36 domains except confidence in healthcare. There were more
depressive patients as severity of POAG increased. There was poor correlation
between quality of life and depression among POAG patients ( r <0.25).
CONCLUSION
Bahasa Malaysia version of GlauQoL 36 and mGDS 14 is a useful tool to assess QoL
and depression of POAG patients in Malaysia. GlauQoL 36 scores increased as the
severity of glaucoma increases suggestive of poorer quality of life. The mGDS 14
score also increases as the severity of glaucoma increases. However, there was poor
correlation between QoL and depression based on the mGDS 14 and GlauQoL 36
questionnaire.
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