Construction Of Human Lymphatic Filariasis Antibody Phage Display Library And Production Of Recombinant Monoclonal Antibodies Against BmR1 And BmSXP Filarial Antigens

Rahumatullah, Anizah (2018) Construction Of Human Lymphatic Filariasis Antibody Phage Display Library And Production Of Recombinant Monoclonal Antibodies Against BmR1 And BmSXP Filarial Antigens. PhD thesis, Universiti Sains Malaysia.

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Abstract

A Global Programme for Elimination of Lymphatic Filariasis aims to eliminate the disease as a public health problem by the year 2020. Brugia Rapid and PanLF Rapid are rapid diagnostic tools that are being used in this programme. They are based on the detection of recombinant proteins BmR1 and BmSXP. The quality of these tests should be well-maintained at all time or even improved as the GPELF progresses and a sensitive and specific test may be needed at the end of the programme and for surveillance post-certification. To address this need, the availability of recombinant monoclonal antibodies to the two recombinant proteins would be very useful.

Item Type:	Thesis (PhD)
Subjects:	R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions:	Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM) > Thesis
Depositing User:	ASM Ab Shukor Mustapa
Date Deposited:	11 Mar 2019 03:03
Last Modified:	12 Apr 2019 05:24
URI:	http://eprints.usm.my/id/eprint/43609

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