Ibraheem, Zaid Osamah
(2011)
Effect Of Palm Oil (Elias Guinensis) Leaf Standardized
Extract On Progression Of Renal Dysfunction And
Arterial Stiffness In Normal And High Fat Diet Fed
Sprague Dawley Rats With Induced Nephrotoxicity.
Masters thesis, Universiti Sains Malaysia.
Abstract
Saturated free fatty acids (SAFFAs) trigger their deleterious effects through inducing the intracellular inflammatory pathway related to insulin resistance. This
results in a constellation of biomedical disorders known as metabolic syndrome. Gentamicin is a widely used aminoglycoside antibiotic. Its nephrotoxic action is
characterized by both proximal convoluted tubules and glomerular membrane damage. The mechanism of nephrotoxicity is closely related to oxidative stress and free radicals
generation.
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