Lew, Kien Seng
(2011)
Synthesis And Characterisation Of Mesoporous Hydroxyapatite
Bioceramics.
Masters thesis, Universiti Sains Malaysia.
Abstract
Mesoporous hydroxyapatite (HA) with smaller pore size in the nano range and with narrower pore size distribution is a better candidate to provide a more favourable drug release profile by exhibiting a more uniform and sustained release. This research was conducted to investigate the drug impregnation and release capability of mesoporous HA synthesised via a self-assembly mechanism between HA and cationic surfactant decyltrimethylammonium bromide (C10TAB) through a co-precipitation route. Different parameters such as pH-control technique, ageing duration, and water ratio were attempted during the synthesis to investigate their respective influence on the sorption properties.
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