Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR

Nassar, Zeyad D. (2011) Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR. Masters thesis, Universiti Sains Malaysia.

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Abstract

Colorectal cancer which involves the colon, rectum and the anal canal is the third most common malignancy worldwide. The disease is characterized by extensive angiogenesis and perturbation of a variety of oncogenes and tumor suppressor genes including, p53, Wnt, hypoxia, NF-кB, Notch, MAP kinase. Targeting one or more of these pathways increases the selectivity of the chemotherapeutic agents as these pathways are important for cancer cells growth and proliferation. Koetjapic acid is a naturally occurring seco-A-ring oleanene triterpene present in the Sandoricum koetjape species that grows in Malaysia and the Southeast Asian region.

Item Type:	Thesis (Masters)
Subjects:	R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions:	Pusat Pengajian Sains Farmasi (School of Pharmacy) > Thesis
Depositing User:	ASM Ab Shukor Mustapa
Date Deposited:	14 Nov 2018 06:48
Last Modified:	12 Apr 2019 05:26
URI:	http://eprints.usm.my/id/eprint/42891

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