Seow , Lay Jing
(2010)
Phytochemical Study, Antimicrobial
And Antiangiogenic Activities Of
The Leaf Extracts Of Gynura Segetum.
Masters thesis, Universiti Sains Malaysia.
Abstract
Gynura segetum (daun dewa in Malay) is a herb from family compositae, reputed to
possess various medicinal values. This plant is believed of value for treating cancer,
diabetes, hypertension, inflammation and skin infection. The leaves of Gynura segetum
were evaluated using quality control parameters, which include gravimetric, thin layer
chromatographic (TLC) and high-performance liquid chromatographic (HPLC) analysis.
The antimicrobial activity of different solvent extracts of leaves of Gynura segetum was
evaluated using agar diffusion method. Ethyl acetate fraction exhibited the highest
inhibitory effect and therefore further fractionation on this fraction was carried out.
Fifteen new subfractions obtained were tested for antimicrobial activity and the MIC of
the active subfractions was determined by tube dilution method.
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