Nor, Natasya Naili Muhamad
(2012)
Screening Of Malaysian Patients With Nasopharyngeal Carcinoma (NPC) Using Comparative Genomic Hybridization (CGH) Technique For Identification Of Specific Genetic Alteration.
Masters thesis, Universiti Sains Malaysia.
Abstract
Nasopharyngeal Carcinoma (NPC) is a malignancy that originates from the epithelial lining of Fossa of Rosen Muller in the nasopharynx. It is a highly prevalent disease in Southern China and Southeast Asia including Malaysia. In this study, the genetic alterations from forty-four NPC patients from five hospitals in Malaysia were screened. Comparative Genomic Hybridization (CGH) technique was used for screening the genetic alterations. CGH is a molecular cytogenetic technique which is used to identify imbalanced genetic alterations that is present in this malignant disease.
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