A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals

Mohamad, Nasir (2011) A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals. PhD thesis, Universiti Sains Malaysia.

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Abstract

Over time, many discoveries revolutionized medicine. Methadone has revolutionized the management of opiate dependence. With MMT, most patients respond well and their health improves. Its complex pharmacology and “opiophobia” however impede its full usefulness. Among the “opiophobics”, alternative therapies with, as an example, Chinese medicines, are frequently sought and advocated. We performed a laboratory and clinical study with the objective of investigating factors that predict successful MMT program, in an effort to improve therapy with methadone and to help us develop guidelines on the optimization of MMT. We also studied the effect of a Chinese herb, BioLitrin in patients maintained on MMT to evaluate its role as an adjunct to MMT.

Item Type:	Thesis (PhD)
Subjects:	R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions:	Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM) > Thesis
Depositing User:	ASM Ab Shukor Mustapa
Date Deposited:	27 Sep 2018 01:51
Last Modified:	12 Apr 2019 05:26
URI:	http://eprints.usm.my/id/eprint/42134

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