Anti-Inflammatory Activity Of Ageratum Conyzoides Linn. , Lantana Camara Linn. And Psidium Guajava Linn. Extracts

Tan, Chong Yee (2009) Anti-Inflammatory Activity Of Ageratum Conyzoides Linn. , Lantana Camara Linn. And Psidium Guajava Linn. Extracts. Masters thesis, Universiti Sains Malaysia.

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Abstract

Dalam percubaan untuk mendapatkan agen anti-inflamasi yang lebih poten tetapi mempunyai kurang kesan sampingan, fraksinasi berpandukan aktiviti dijalankan terhadap Ageratum conyzoides Linn., Lantana camara Linn., dan Psidium guajava Linn.. Ekstrak-ekstrak tersebut disaring dengan model haiwan tapak kaki belakang tikus aruhan ‘carrageenan’. Pada permulaannya, model ini dioptimasikan untuk memperolehi agen pengampaian yang paling baik untuk agen anti-inflamasi yang tidak larut air seperti indometasin / ekstrak dan menentukan jenis haiwan ujikaji yang paling peka terhadap perencatan pembentukan edema oleh indometasin. In an attempt to seek for more potent and less side effects anti-inflammatory agent(s), activity guided fractionation was performed on Ageratum conyzoides Linn., Lantana camara Linn. and Psidium guajava Linn. extracts. The extracts were screened using animal model carrageenan induced hind paw oedema. The model was optimised first to find the best suspending agent for water insoluble antiinflammatory agent indomethacin/extracts and to determine the type of experimental animals most sensitive to indomethacin inhibition of oedema.

Item Type: Thesis (Masters)
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: Pusat Pengajian Sains Farmasi (School of Pharmacy) > Thesis
Depositing User: Mr Mohammad Harish Sabri
Date Deposited: 17 Aug 2018 07:54
Last Modified: 12 Apr 2019 05:27
URI: http://eprints.usm.my/id/eprint/41379

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