Mostafa, Hamza Mohamed Amin and Mostafa, Arwa Mohamed Amin and Arif, Nor Hayati and Chin, Hoe Teh and Ibrahim, Baharudin
(2014)
Identification of Alcohol-Dependence Biomarkers in plasma by using Metabolomics Analysis.
In: Asian Conference on Clinical Pharmacy, November 2014, Terengganu, Malaysia.
Abstract
The main clinical methods to diagnose Alcohol-dependence (AD) in clinical practice currently depend on AD assessment questionnaires and some biomarkers such as Carbohydrate-Deficient Transferrin (CDT), Gamma Glutamyl Transferase (GGT) and Phosphatidylethanol (PEth). These two methods have been shown to have lack of specificity and sensitivity. Metabolomics technique by using nuclear magnetic resonance spectroscopy (NMR) of plasma can help us to identify novel biomarkers which could help in the more accurate diagnosis of AD.
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