Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers

Mostafa, Hamza Mohamed Amin and Mostafa, Arwa Mohamed Amin and Arif, Nor Hayati and Chin, Hoe Teh and Murugaiyah, Vikneswaran a/l and Ibrahim, Baharudin (2014) Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers. In: The Medical Journal of Penang Hospital-Penang Research Day, May 2014, Pulau Pinang, Malaysia.

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The clinical diagnosis of alcohol-dependence (AD) currently relies on AD assessment questionnairesand biomarkers such as Carbohydrate-DeficientTransferrin (CDT), Gamma Glutamyl Transferase (GGT) and Phosphatidylethanol (PEth). However, both methods of diagnosis lackspecificity and sensitivity. Metabolic fingerprinting using nuclear magnetic resonance spectroscopy (NMR)of plasma may give us a novel andaccurate method for the diagnosis of the disease. Our primary objective was to identify the metabolites/biomarkers that could discriminate between subjects diagnosed asAD, social drinkersnon-dependent and healthy control.

Item Type: Conference or Workshop Item (Paper)
Subjects: R Medicine > RC Internal medicine
Divisions: Pusat Pengajian Sains Farmasi (School of Pharmacy) > Conference or Workshop Item
Depositing User: Administrator Automasi
Date Deposited: 05 Jul 2018 04:25
Last Modified: 05 Jul 2018 04:25

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