Hla Genetic Profile of Malay Sub-ethnic Groups of Peninsular Malaysia as Determined by Pcr-ssp and Sbt Methods

Shahril, Allia (2016) Hla Genetic Profile of Malay Sub-ethnic Groups of Peninsular Malaysia as Determined by Pcr-ssp and Sbt Methods. PhD thesis, USM.

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Abstract

Kepulauan Indo-Melayu merupakan tanah air bagi penduduk penutur Austronesia yang dikenali sebagai orang Melayu.Sekarang, definisi Melayu adalah terbatas kepada penduduk yang tinggal di Malaysia.Oleh kerana asal-usul orang Melayu di Malaysia yang berbeza dari pelbagai bahagian KepulauanIndo-Melayu, terdapat banyak sub-etnik Melayu yang tinggal di Malaysia.Objektif utama kajian ini adalah untuk mengkaji taburan alel HLA dan haplotaip dalam kumpulan sub-etnik Melayu.Taburan alel-alel antigen leukosit manusia (HLA) kelas I dan II telah disiasat pada 222 individu Melayu yang tidak mempunyai hubungan persaudaraan daripada enam kumpulan sub-etnik Melayu iaitu Kelantan (64), Champa (42), Patani (30), Kedah (30), Aceh (30) dan Mandailing (30) di Semenanjung Malaysia. The Indo-Malay Archipelago is the homeland of the Austronesian speaking population known as the Malays. Now, the definition of Malay is confine to the population residing in Malaysia. Due to the different origin of the Malays in Malaysia from various parts of the Malay Indo-Archipelogo, there are many Malay sub-ethnic groups living in Malaysia. The main objective of this research is to study the distribution of the HLA alleles and haplotypes in the Malay sub-ethnic groups. The human leukocyte antigen (HLA) class I and II allele distributions were investigated in 222 unrelated Malay individuals belonging to six Malay sub-ethnic groups namely Kelantan (64), Champa (42), Patani (30), Kedah (30), Aceh (30) and Mandailing (30) in Peninsular Malaysia.

Item Type: Thesis (PhD)
Subjects: R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Kesihatan (School of Health Sciences) > Thesis
Depositing User: ARKM Al Rashid Automasi
Date Deposited: 28 Jun 2018 07:56
Last Modified: 28 Jun 2018 07:56
URI: http://eprints.usm.my/id/eprint/40844

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