Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation

Chan , Guat Choo (2017) Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation. Masters thesis, Universiti Sains Malaysia.

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    Abstract

    Kejadian kanser tiroid differentiated telah meningkat dengan ketara di seluruh dunia. Tiyroglobulin (Tg) serum dan imbasan seluruh badan selepas rawatan radioiodin (I-131 Dx WBS) adalah dua jenis siasatan susulan yang dijalani selepas rawatan kanser di peringkat awal (pembedahan pembuangan seluruh tiroid dan pemusnahan sisa tiroid dengan radioiodin). Kajian ini bertujuan untuk menilai korelasi dan nilai ramalan Tg terangsang (sTg) 6 bulan selepas pemusnahan sisa tiroid dengan radioiodin untuk menentukan kewujudan penyakit berstruktur (SED) dalam I-131 Dx WBS. Jika sTg mempunyai nilai ramalan yang sangat tinggi terhadap kewujudan penyakit, ia boleh menggantikan I-131 Dx WBS untuk menilai kewujudan penyakit. Nilai ulangan sTg juga ditentukan bagi dua sampel berlainan yang diambil selepas tempoh 6 bulan. Metodologi: The incidence of differentiated thyroid cancer (DTC) has increased substantially worldwide in the past four decades. Serum thyroglobulin (Tg) and radioiodine diagnostic whole body scan (131-I Dx WBS) are two main surveillance tools to investigate for persistent disease after initial therapy - total thyroidectomy followed by radioiodine remnant ablation (RRA). This study evaluates the correlation, predictive value and reliability of stimulated thyroglobulin (sTg) for detection of structural evidence of disease (SED) in 131-I Dx WBS 6 months after initial therapy in the Nuclear Medicine Department Penang Hospital (NMDPH).

    Item Type: Thesis (Masters)
    Subjects: R Medicine > RK Dentistry > RK1-715 Dentistry
    Divisions: Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute) > Thesis
    Depositing User: Mr Firdaus Mohamad
    Date Deposited: 25 May 2018 09:31
    Last Modified: 25 May 2018 09:31
    URI: http://eprints.usm.my/id/eprint/40593

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