Md Supian, Badrul Hisham
(2015)
C-reactive protein : determinant value predicting
length of stay in dengue patient attending emergency
department HUSM Kubang Kerian.
Masters thesis, Universiti Sains Malaysia.
Abstract
Title: C -reactive Protein: Determinant value predicting length of stay in dengue patient
attending Emergency Department HUSM Kubang Kerian, Kelantan.
Background: C-reactive protein is simple and cheap laboratory parameters that can be
use in Emergency Department or inpatient ward to predict hospital stay and severity of
disease.
Objectives: To determine association between C-reactive protein between length of
stay, severity of disease and survival rate of dengue patient in Emergency Department.
Methodology: A cross-sectional study of adult confirmed dengue patients (age
between 18-70 years) presented to ED Hospital Universiti Sains Malaysia then
subsequently admitted to the medical ward. Length of stay, severity and survival rate of
dengue patient was assessed in relation to C-reactive protein level.
Results: Fifty patients were included during study period of 6 months. From this study,
it showed that there was significant increase level of C-reactive protein with longer
hospital stay and in severe dengue patient. For this study, mean length of stay was 4
days for patient with high level of c-reactive protein. However, from Mann Whitney U
test, it was shown that there was no significant correlation between CRP level and
length of stay with p-value of 0.28. There was also, higher level of C-reactive protein
in patient who developed severe dengue. But from Chi-square test, was no significant
correlation between CRP level with risk of develop into severe dengue.
Conclusion: In conclusion, despite of few limitations in our study has shown no
correlation between CRP level and length of stay, severity of clinical course or
mortality in dengue patient .
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