Tengku Hussain, Tengku Hasnita
(2015)
A study on the reliability of bilispect to measure bilirubin levels in term neonates.
Masters thesis, Universiti Sains Malaysia.
Abstract
INTRODUCTION :
Neonatal jaundice commonly occurred in newborn babies. The monitoring of it becomes very important to prevent complications. Blood taking is an invasive
procedure that associated with pain in newborn. Availability of new devices with
updated technology leading to non invasive monitoring in newborn. Development of Bilispect as transcutaneous bilirubinometer gave opportunities to reduce blood
taking in newborn.
OBJECTIVES:
To test reliability of Bilispect in monitoring bilirubin level of term babies, pre and
post-phototherapy.
METHODS:
This study was a cross sectional study in HUSM for term babies with neonatal
jaundice who fulfilled inclusion criteria.
RESULT:
There were total of 74 babies involved in this study. Among these, 44 babies involved in both part pre-phototherapy and post-phototherapy reading. Additional
of 15 babies only involved in one part of the study, either pre-phototherapy or post-phototherapy. Total of 59 samples were collected in each part. The gender
distribution was equal for pre and post-phototherapy group. The mean age was 3.9
days with mean gestation was 39weeks. The differences of serum bilirubin and
Bilispect reading for pre-phototherapy result was from -132.6 to 190.8. For the
post-phototherapy result, the differences value range from -45.2 to 164.0. Pearson
correlation value derived were weak positive correlation (0.466) and moderate
positive correlation (0.566) for pre and post-phototherapy respectively. The Bland
Altman plot degree of agreement between these methods were 93.22% for prephototherapy
and 96.6% for post-phototherapy.
CONCLUSION:
The results of this study showed that the Bilispect device had a statistically
significant correlation with the serum bilirubin values. However for too many
samples the differences between the two were too big to support clinical usage of
the Bilispect at this point in time.
In conclusion serum bilirubin is still a gold
standard for jaundice monitoring in newborn.
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