Suppression Of Aml1/ETO Via siRNA Mediated Gene Knockdown And Its Effects On FOXO3 AND c-Myc Expression In Aml t (8,21) Cells

Ong, Si Min (2017) Suppression Of Aml1/ETO Via siRNA Mediated Gene Knockdown And Its Effects On FOXO3 AND c-Myc Expression In Aml t (8,21) Cells. Masters thesis, Universiti Sains Malaysia.

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    Abstract

    Akut mieloid leukemia (AML) dengan t (8,21) translocation adalah salah satu kelainan karyotypic yang paling kerap diperhatikan dalam AML yang menghasilkan gen bergabung onko-protein, AML1/ETO. siRNA adalah alat penggangguan RNA (RNAi) yang biasa digunakan untuk mendorong pembubaran jangka pendek gen pengekodan protein Acute Myeloid Leukemia (AML) with t (8,21) translocation is one of the most frequent karyotypic abnormalities observed in AML that results in formation of fusion onco-protein, AML1/ETO. siRNA is a commonly used RNA interference (RNAi) tool to induce short-term silencing of protein coding genes

    Item Type: Thesis (Masters)
    Subjects: R Medicine > RK Dentistry > RK1-715 Dentistry
    Divisions: Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute) > Thesis
    Depositing User: Mr Erwan Roslan
    Date Deposited: 07 Mar 2018 08:57
    Last Modified: 17 May 2018 11:09
    URI: http://eprints.usm.my/id/eprint/39313

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