Suppression Of Aml1/ETO Via siRNA Mediated Gene Knockdown And Its Effects On FOXO3 AND c-Myc Expression In Aml t (8,21) Cells

Ong, Si Min (2017) Suppression Of Aml1/ETO Via siRNA Mediated Gene Knockdown And Its Effects On FOXO3 AND c-Myc Expression In Aml t (8,21) Cells. Masters thesis, Universiti Sains Malaysia.

Preview

PDF Download (541kB) | Preview

Abstract

Akut mieloid leukemia (AML) dengan t (8,21) translocation adalah salah satu kelainan karyotypic yang paling kerap diperhatikan dalam AML yang menghasilkan gen bergabung onko-protein, AML1/ETO. siRNA adalah alat penggangguan RNA (RNAi) yang biasa digunakan untuk mendorong pembubaran jangka pendek gen pengekodan protein Acute Myeloid Leukemia (AML) with t (8,21) translocation is one of the most frequent karyotypic abnormalities observed in AML that results in formation of fusion onco-protein, AML1/ETO. siRNA is a commonly used RNA interference (RNAi) tool to induce short-term silencing of protein coding genes

Item Type:	Thesis (Masters)
Subjects:	R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions:	Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis
Depositing User:	Mr Erwan Roslan
Date Deposited:	07 Mar 2018 00:57
Last Modified:	12 Apr 2019 05:25
URI:	http://eprints.usm.my/id/eprint/39313

Actions (login required)

View Item