Formulation And Evaluation Of Colchicine Loaded Ethosomal Gel For Transdermal Delivery

M.Abdulbaqi Almalla Yousif, Ibrahim (2017) Formulation And Evaluation Of Colchicine Loaded Ethosomal Gel For Transdermal Delivery. Masters thesis, Universiti Sains Malaysia.

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    Abstract

    Colchicin digunakan untuk rawatan gout, pseudo-gout dan demam Mediterranean. Ia diketahui mempunyai terapetik indeks rendah dan biokeperolehan oral rendah yang disebabkan oleh kesan laluan pertama yang teruk, dan ia juga dikaitkan dengan kesan sampingan gastrousus teruk berikutan pemberian oral Colchicine is used for the treatment of gout, pseudo-gout and familial Mediterranean fever. It is known to have low therapeutic index and low oral bioavailability due to extensive first pass effect, and also associated with sever gastrointestinal side effects following oral administration

    Item Type: Thesis (Masters)
    Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
    Divisions: Pusat Pengajian Sains Farmasi (School of Pharmacy) > Thesis
    Depositing User: Mr Erwan Roslan
    Date Deposited: 20 Feb 2018 14:46
    Last Modified: 17 May 2018 11:09
    URI: http://eprints.usm.my/id/eprint/39054

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