Yeong, Yeh Lee and Bhaskar, Shalini
(2011)
An Unusual Association between Unilateral Intracranial Vessels Occlusion with Iron Deficiency Anaemia and Alpha-Thalassemia Trait: A Case Report.
Case Reports in Medicine, 2011 (271560).
pp. 1-4.
ISSN 1687-9627
Abstract
We report a 33-year-old Malay woman presented with acute left dense hemiparesis and an NIHSS score of 11/15. Computed
tomography (CT) scan brain showed a massive right middle cerebral artery (MCA) territory infarct. The right internal
carotid artery (ICA) and right proximal MCA were shown occluded from digital substraction angiography (DSA). Carotid
dissection, carotid canal anomaly, and intercavernous communication were systematically ruled out. She had no risk factors
for atherosclerosis. The connective tissue screening and thrombophilic markers were negative. However, she was anaemic on
admission and subsequent investigations revealed that she had alpha-thalassemia and iron deficiency anaemia. The right ICA
remained occluded from a repeat CT cerebral angiogram after one year, but otherwise she was neurologically stable. This case
illustrates an unusual association between intracranial vessel occlusion with iron deficiency anaemia and alpha-thalassemia trait.
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