Go, Eng Soon
(2001)
Expressin of Interleukin 4, Interleukin 4 Receptor and IL-4 Receptor Related GP200-MR6 Molecule in Pterygium and Normal Bulbar Conjunctiva Tissue.
Masters thesis, Universiti Sains Malaysia.
Abstract
IL-4 has been shown to have anti-tumoural activity in many cell lines. IL-4 needs to
bind with IL-4 Receptor to exert its action. Down-regulation of IL-4 associated gp200-
MR6 expression has been associated with increasingly malignant tissues.
Fifty-one pterygium and forty-one superior bulbar conjunctiva tissues from patients
with pterygium, along with fourteen conjunctiva samples from pterygium-free subjects
are subjected to immunohistochemical analysis to detennined the expression of IL-4,
IL-4 receptor and IL-4 receptor associated gp200-MR6 molecule.
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