Correlation of interleukin 31 serum levels in patients with atopic dermatitis, allergic rhinitis and atopic asthma

Mohd @ Muhammad Amin, Siti Noor Syuhada (2013) Correlation of interleukin 31 serum levels in patients with atopic dermatitis, allergic rhinitis and atopic asthma. Masters thesis, Universiti Sains Malaysia.

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    Abstract

    Interleukin 31 (IL-31), merupakan salah satu daripada sitokin yang menjadi pengawal atur yang penting terhadap tindak balas TH2. Kajian terdahulu telah dilakukan oleh Zhang et al. (2008), untuk mengukur paras IL-31 di kalangan atopic dermatitis (AD). Walaubagaimanapun, paras IL-31 di kalangan allergic rhinitis (AR) dan atopic asthma (AA) adalah masih tidak jelas. Objektif-objektif dalam kajian “cross sectional” ini adalah untuk mengukur paras IL-31 di kalangan AD, AR dan AA, untuk mengukur korelasi antara IL-31 dan faktor-faktor yang mempengaruhi penyakit, untuk mengukur IL-31 dan tahap keterukan penyakit dan untuk mengukur paras IL-31 dan pruritus di kalangan pesakit. Interleukin 31 (IL-31), is one of the cytokines which appears to be an important regulator of TH2 responses. Previous study has been done by Zhang et al. (2008), to determine IL-31 serums levels in atopic dermatitis (AD). However, the serum levels of IL-31 in allergic rhinitis (AR) and atopic asthma (AA) is still unclear. The objectives of this cross sectional study are to determine IL-31 serum levels in AD, AR and AA, to study the association between IL-31 and predisposing factors with allergic diseases, to correlate IL-31 levels and the severity of allergic diseases and to compare IL-31 levels and pruritus in patients with allergic diseases.

    Item Type: Thesis (Masters)
    Subjects: R Medicine > R Medicine (General) > R5-130.5 General works
    Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences)
    Depositing User: Mr Noorazilan Noordin
    Date Deposited: 07 Sep 2017 12:24
    Last Modified: 07 Sep 2017 12:24
    URI: http://eprints.usm.my/id/eprint/36398

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