Nik Zaid, Nik Azlan
(2001)
Topical latanoprost (PGF2 analogue) for the prevention of immediate increase in intraocular pressure after cataract extraction.
Masters thesis, Universiti Sains Malaysia.
Abstract
Kami telah menjalankan satu kajian ke atas kesan analog Prostaglandin PGF2o. terhadap
tekanan intraokular mata pesakit yang menjalani pembedahan katarak. Sebanyak 72 mata
pesakit yang menjalani pembedahan katarak menggunakan teknik endocapsular beserta
implantasi kanta intra-okular menggunakan bahan viskoelastik, telah dibahagikan kepada
dua kumpulan secara rawak. Sebanyak 36 mata pesakit di dalam kumpulan latanoprost
menerima ubat titis latanoprost 0.005% sebaik selesai pembedahan sementara 36 mata
pesakit di dalam kumpulan kontrol menerima ubat titis tetrahydrozoline hydrochloride
(optizolin). Aspek-aspek lain rawatan dan pembedahan bagi kedua-dua kumpulan adalah
sama. Tekanan intraokular telah diukur sebelum pembedahan (pra-pembedahan) dan 3, 6, 9
dan 24 jam selepas pembedahan.
The effect of prostaglandin analogue PGF2a. was tested in immediate post-operative
cataract extraction eyes. Seventy-two eyes undergoing endocapsular cataract extraction
with capsular bag intraocular lens implantation using viscoelastic substance were randomly
assigned into two groups. Thirty-six eyes in latanoprost group received 0.005o/o latanoprost
eye drop at the end of the operative procedure while another thirty-six eyes in control group
received a topical drop of placebo ( tetrahydrozoline hydrochloride) similarly. In all other
respects the eyes were treated identically. Intraocular pressure (lOP) was measured preoperatively
and at 3, 6, 9 and 24 hours post-operatively.
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